Metabolic profile of diabetic rats submitted to chronic physical exercise

Metabolic profile of diabetic rats submitted to chronic physical exercise

Authors

  • Kelly Elizeu da Silva Curso de Ciências Biológicas – UNESP – Campus de Rio Claro SP
  • Ricardo José Gomes Departamento de Educação Física IB UNESP – Rio Claro SP
  • Helton André Hermini Departamento de Educação Física IB UNESP – Rio Claro SP
  • José Roberto Moreira de Azevedo Departamento de Educação Física IB UNESP – Rio Claro SP
  • Eliete Luciano Departamento de Educação Física IB UNESP – Rio Claro SP

DOI:

https://doi.org/10.5016/388

Keywords:

Diabetes, metabolismo, exercício crônico, estreptozotocina.

Abstract

The aim of the present study was to examine the effects of physical exercise on the metabolic profile in diabetic rats induced by streptozotocin. Male Wistar rats were divided into 4 groups, sedentary control (SC), trained control (TC), sedentary diabetic (SD) and trained diabetic (TD). Diabetes was induced by Streptozotocin (50 mg/kg b.w. i.v.). The training program consisted of swimming 5 days/week, 1 h/day, supporting a load of 5 % body weight for 8 weeks. The diabetic groups (sedentary and trained) showed hyperglycemia. The training reduced serum AGL in both, diabetic and control groups. Besides, the training increased total proteins and muscle glycogen in control group. It was concluded that diabetes (by streptozotocin) induced some alterations on metabolic profile and physical training promoted important metabolic adaptations in Wistar rats.

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Published

2007-06-19

Issue

V. 10, N. 3 (2004)

Section

Original Articles

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